The interior, which was altered several times, offers very interesting works of art, such as “The Annunciation” by Federico Barocci, finished by his pupil Ventura Mazza, or the paintings on the vault above the high altar, by Gubbio artist Francesco Allegrini (17th c.). Still visible in the “Sepolcro” (“Sepulchre”) underneath are 15th c. frescoes with “Stories of the Passion” by an anonymous pupil of Nelli (some of these frescoes have been transferred to the Diocesan Museum).