The archaeological section exhibits artefacts of the Roman era and early Middle Ages; in the adjoining rooms are to be found examples of paintings on wood by the Gubbio artist Mello.
Fifteenth century painting is represented by works from the studios of Ottaviano Nelli and Taddeo di Bartolo, as well as by a series of detached frescoes representing scenes from Christ’s Passion. In the collection of vestments and liturgical furnishings, the jewel in the crown is a finely decorated Flemish cope from the Renaissance period. Paintings by artists such as Benedetto Nucci, Giovanni M. Baldassini and Girolamo Danti complete the art collection.

On the ground floor of the museum one can see the old “Canons’ Barrel”, a genuine curiosity in the history of winemaking, with its capacity of 19,350 litres.